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To treat advanced stage liver cancer with Canelim Capsules combined with hepatic transcatheter artery chemoembolization (TAE)

Zhou B. Gang, et al. Hospital of NingXia Autonomous Region

Result:

Table 1--Effectiveness

Croup
Cases
CR
PR
MR
SD
PD
Total Effective % (CR+PR)
Canelim
31
10
15
5
1
0
80.64
Control
25
7
10
5
1
2
68.00

Table 2--Tumor shrinkage and survival rate

Group
Cases
Tumor shrinkage
Survival rate
3 months
6 months
1 year
Canelim
31
29 (93.55%)
31 (100%)
28 (90.32%)
27 (87.09%)
Control
25
22 (88.0%)
24 (96.0%)
22 (88.0%)
21 (84.0%)

Table 3--Symptom improvement and AKP score

Croup
Cases
Greatly improved
Partially improved
No improvement
Improved rate (%)
AKP score devalued (%)
Canelim
31
16
9
6
80.64
80
Control
25
9
7
9
64.0
58.33

Treatment methods:
Control Group:
TAE, Seldinger's method. 5-FU + MMC +ADR, once a month, average 3 times.
Canelim Group: TAE + Canelim Capsules (6*3 times/day, 3 months continuously)

Discuss:

Table 1--Effectiveness: The total effective rate in Canleim group is 80.64%. Compared with that in control group, the difference is significant (p<0.05).
Table 2--Tumor shrinkage and survival rate : The tumor shrinkage rate and survival rate are both higher in Canelim group than the equals in the control group, though the difference is not parent.
Table 3--Symptom improvement and AKP score : 80.64% in Canelim group had symptoms improved. Compared with the rate in control group, the difference is significant. The change in AKP score states the same tendency.

Conclusion:
Canelim Capsules combined with TAE method could take advantage of each other. It is a good effective method for treating advanced liver cancer and deserves to be recommended.


 

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